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As research continues and our understanding of the aging process deepens, new and exciting therapies, medications, and treatments are constantly being developed to impact the pillars of aging. There are several innovations that are transforming anti-aging science and may hold great promise as part of your wellness regimen.
This is an FDA-approved diabetic medication, but it also tends to curb food intake and reduce weight due to its impact on the hypothalamus. Calorie restriction is considered the most reliable, though not practical, way of extending lifespan and healthspan. On a biochemical level Metformin is thought to work through AMPK activation and mTor inhibition. Clinically it has positive effects on cholesterol levels, can lower inflammation, may help prevent some cancer, and has a long history of safety.
NAD is a derivative of Niacin, or vitamin B3, that serves the vital role of producing cellular energy in the human body. Simply put, there is no life without NAD+. Like many things, NAD+ levels decline with age, which has been linked to the development of neurodegenerative disorders, metabolic disease, and cancer.
While it’s well known as a treatment for bipolar disorder in high doses, low-dose nutritional lithium has health-promoting properties and is used in a supplemental form in wellness clinics. Lithium seems to protect cells from toxic compounds, provides resistance to stress, and has shown longevity benefits in animal models.
This polyphenol was one of the earliest anti-aging molecules that showed significant promise in promoting healthspan and longevity. Resveratrol is an antifungal chemical found in some of our favorite foods, such as grapes, blueberries, and red wine.
Resveratrol is sold as a dietary supplement and is used in many wellness centers to help control polycystic ovarian syndrome (PCOS). It’s neuroprotective and has shown promise in addressing cardiovascular disease, diabetes, and metabolic syndrome.
This is a naturally occurring sex hormone produced in the adrenal glands. Its health-promoting attributes include improving bone and heart health and helping with glucose control. It has shown some longevity promise by decreasing the effect of inflammation (interleukin-6) and limiting the negative effect of glucose in the body.
Growth hormone research has shown it can improve human health by reducing adiposity, increasing muscle mass, and improving skin thickness and bone density in elderly populations. It is also thought that growth hormone may help treat age-related conditions of frailty and sarcopenia. However, growth hormone use has its complexities. While growth hormone is not legal to prescribe off-label in the United States, growth-hormone releasing hormone is readily available for off-label use. Growth hormone has also been abused in professional sports as a performance enhancer and there have been some signs of health concerns making it a complex hormone. The jury is still out but it remains an exciting area of research.
An exciting study led by Dr. Greg Fahy of Intervene Immune and Dr. Steve Horvath at the University of California in Los Angeles found that a unique combination of growth hormones and two common diabetic medications may actually reverse biological age and partially regrow the thymus gland. Based on this research, we have made this genetic test available to patients at Aspire Regenerative. This research is still in the early stages but shows that exciting anti-aging treatments are on the horizon, and we will be watching them closely.
Learn more about Aspire Regnerative’s Anti-Aging Treatments!